7) Bayonetta
Certainly one of the least farfetched theories on this list would be that of considering how a violent witch that fights against a race of angels could become a great gaming villain. After all, she’s a violent witch that fights against a race of angels.
Bayonetta’s past is such that her birth caused a mass conflict between previously peaceful clans, leading to her being expelled from their world and sealed away for 500 years. This results in the angels becoming her antagonists, but who’s to say which of these clans is actually the good and which is the evil?
Tradition dictates that angels are good and witches are evil, while Bayonetta’s aggressive nature and use of “torture attacks” certainly suggests the same is true. Fighting against such a powerful and ruthless foe would be an intriguing twist on the Bayonetta formula, and she certainly has the fiery personality to make her a formidable villain!